One carbon metabolism and glutathione (GSH) synthesis and metabolism. Download Scientific Diagram Cells need a steady supply of antioxidants to defend themselves, and glutathione is the body's master defender. Yet, daily stress and ageing can deplete glutathione faster than we can make it. NAC + Hepatocyte glutathione S transferase mu 2 prevents non alcoholic steatohepatitis by suppressing ASK1 signaling Journal of Hepatology Figure 2 from Glutathione synthesis. Semantic Scholar